Publications

Wunderli, S. L.; Widmer, J.; Amrein, N.; Foolen, J.; Silvan, U.; Leupin, O.; Snedeker, J. G. Minimal Mechanical Load and Tissue Culture Conditions Preserve Native Cell Phenotype and Morphology in Tendon-a Novel Ex Vivo Mouse Explant Model. Journal of Orthopaedic Research 2018, 36 (5), 1383–1390. https://doi.org/10.1002/jor.23769.

Bernal, L. M. B.; Schmidt, I. T.; Vulin, N.; Widmer, J.; Snedeker, J. G.; Cattin, P. C.; Zam, A.; Rauter, G. Optimizing controlled laser cutting of hard tissue (bone). at - Automatisierungstechnik 2018, 66 (12), 1072–1082. https://doi.org/10.1515/auto-2018-0072.

Scheibler, A.-G.; Götschi, T.; Widmer, J.; Holenstein, C.; Steffen, T.; Camenzind, R. S.; Snedeker, J. G.; Farshad, M. Feasibility of the Annulus Fibrosus Repair with in Situ Gelating Hydrogels – A Biomechanical Study. PLOS ONE 2018, 13 (12), e0208460. https://doi.org/10.1371/journal.pone.0208460.

Cornaz, F.; Fasser, M.-R.; Spirig, J. M.; Snedeker, J. G.; Farshad, M.; Widmer, J. 3D Printed Clamps Improve Spine Specimen Fixation in Biomechanical Testing. J Biomech 2019, 98, 109467. https://doi.org/10.1016/j.jbiomech.2019.109467.

Widmer, J.; Fornaciari, P.; Senteler, M.; Roth, T.; Snedeker, J. G.; Farshad, M. Kinematics of the Spine Under Healthy and Degenerative Conditions: A Systematic Review. Ann Biomed Eng 2019, 47 (7), 1491–1522. https://doi.org/10.1007/s10439-019-02252-x.

Cornaz, F.; Widmer, J.; Snedeker, J. G.; Spirig, J. M.; Farshad, M. Cross-Links in Posterior Pedicle Screw-Rod Instrumentation of the Spine: A Systematic Review on Mechanical, Biomechanical, Numerical and Clinical Studies. Eur Spine J 2020, 30 (1), 34–49. https://doi.org/10.1007/s00586-020-06597-z.

Widmer, J.; Fasser, M.-R.; Croci, E.; Spirig, J.; Snedeker, J. G.; Farshad, M. Individualized Prediction of Pedicle Screw Fixation Strength with a Finite Element Model. Computer Methods in Biomechanics and Biomedical Engineering 2020, 23 (4), 155–167. https://doi.org/10.1080/10255842.2019.1709173.

Schoenenberger, A. D.; Tempfer, H.; Lehner, C.; Egloff, J.; Mauracher, M.; Bird, A.; Widmer, J.; Maniura-Weber, K.; Fucentese, S. F.; Traweger, A.; Silvan, U.; Snedeker, J. G. Macromechanics and Polycaprolactone Fiber Organization Drive Macrophage Polarization and Regulate Inflammatory Activation of Tendon in Vitro and in Vivo. Biomaterials 2020, 249, 120034. https://doi.org/10.1016/j.biomaterials.2020.120034.

Widmer, J.; Cornaz, F.; Scheibler, G.; Spirig, J. M.; Snedeker, J. G.; Farshad, M. Biomechanical Contribution of Spinal Structures to Stability of the Lumbar Spine—Novel Biomechanical Insights. The Spine Journal 2020, 20(10), 1705–1716. https://doi.org/10.1016/j.spinee.2020.05.541.

Caprara, S.; Carrillo, F.; Snedeker, J. G.; Farshad, M.; Senteler, M. Automated Pipeline to Generate Anatomically Accurate Patient-Specific Biomechanical Models of Healthy and Pathological FSUs. Front. Bioeng. Biotechnol.2021, 9. https://doi.org/10.3389/fbioe.2021.636953.

Caprara, S.; Fasser, M.-R.; Spirig, J. M.; Widmer, J.; Snedeker, J. G.; Farshad, M.; Senteler, M. Bone Density Optimized Pedicle Screw Instrumentation Improves Screw Pull-out Force in Lumbar Vertebrae. Computer Methods in Biomechanics and Biomedical Engineering 2021, 25 (4), 464–474. https://doi.org/10.1080/10255842.2021.1959558.

Fasser, M.-R.; Jokeit, M.; Kalthoff, M.; Gomez Romero, D. A.; Trache, T.; Snedeker, J. G.; Farshad, M.; Widmer, J. Subject-Specific Alignment and Mass Distribution in Musculoskeletal Models of the Lumbar Spine. Front Bioeng Biotechnol 2021, 9, 721042. https://doi.org/10.3389/fbioe.2021.721042.

Farshad, M.; Frey, A.; Jentzsch, T.; Betz, M.; Widmer, J.; Spirig, J. M. Reducing the Kyphosis Effect of Anterior Short Thoracolumbar/Lumbar Scoliosis Correction with an Autograft Fulcrum Effect. BMC Musculoskeletal Disorders 2021, 22 (1), 216. https://doi.org/10.1186/s12891-021-04083-1.

Cornaz, F.; Widmer, J.; Farshad-Amacker, N. A.; Spirig, J. M.; Snedeker, J. G.; Farshad, M. Intervertebral Disc Degeneration Relates to Biomechanical Changes of Spinal Ligaments. The Spine Journal 2021. https://doi.org/10.1016/j.spinee.2021.04.016.

Götschi, T.; Widmer, J.; Cornaz, F.; Kimenai, J.; Spirig, J. M.; Snedeker, J. G.; Farshad, M. Region- and Degeneration Dependent Stiffness Distribution in Intervertebral Discs Derived by Shear Wave Elastography. Journal of Biomechanics 2021, 121, 110395. https://doi.org/10.1016/j.jbiomech.2021.110395.

Spirig, J. M.; Winkler, E.; Cornaz, F.; Fasser, M.-R.; Betz, M.; Snedeker, J. G.; Widmer, J.; Farshad, M. Biomechanical Performance of Bicortical versus Pericortical Bone Trajectory (CBT) Pedicle Screws. Eur Spine J2021. https://doi.org/10.1007/s00586-021-06878-1.

Cornaz, F.; Widmer, J.; Farshad-Amacker, N. A.; Spirig, J. M.; Snedeker, J. G.; Farshad, M. Biomechanical Contributions of Spinal Structures with Different Degrees of Disc Degeneration. Spine 2021, Publish Ahead of Print. https://doi.org/10.1097/BRS.0000000000003883.

Cornaz, F.; Widmer, J.; Fasser, M.-R.; Snedeker, J. G.; Matsukawa, K.; Spirig, J. M.; Farshad, M. Is a Cross-Connector Beneficial for Single Level Traditional or Cortical Bone Trajectory Pedicle Screw Instrumentation? PLOS ONE 2021, 16 (6), e0253076. https://doi.org/10.1371/journal.pone.0253076.

Roth, T.; Rahm, S.; Jungwirth-Weinberger, A.; Süess, J.; Sutter, R.; Schellenberg, F.; Taylor, W. R.; Snedeker, J. G.; Widmer, J.; Zingg, P. Restoring Range of Motion in Reduced Acetabular Version by Increasing Femoral Antetorsion – What about Joint Load? Clinical Biomechanics 2021, 87, 105409. https://doi.org/10.1016/j.clinbiomech.2021.105409.

Cornaz, F.; Burkhard, M.; Fasser, M.-R.; Spirig, J. M.; Snedeker, J. G.; Farshad, M.; Widmer, J. 3D Printed Clamps for Fixation of Spinal Segments in Biomechanical Testing. Journal of Biomechanics 2021, 125, 110577. https://doi.org/10.1016/j.jbiomech.2021.110577.

Widmer, J.; Cornaz, F.; Farshad-Amacker, N. A.; Snedeker, J. G.; Spirig, med. J. M.; Farshad, M. Hydrostatic Integrity of the Intervertebral Disc Assessed by MRI. Journal of Biomechanics 2021, 127, 110661. https://doi.org/10.1016/j.jbiomech.2021.110661.

Burkhard, M. D.; Cornaz, F.; Spirig, J. M.; Wanivenhaus, F.; Loucas, R.; Fasser, M.-R.; Widmer, J.; Farshad, M. Posterior Spinal Instrumentation and Decompression with or without Cross-Link? North American Spine Society Journal (NASSJ) 2021, 8, 100093. https://doi.org/10.1016/j.xnsj.2021.100093.

Cornaz, F.; Farshad, M.; Widmer, J. Location of Pedicle Screw Hold in Relation to Bone Quality and Loads. Frontiers in Bioengineering and Biotechnology 2022, 10.

Fasser, M.-R.; Kuravi, R.; Bulla, M.; Snedeker, J. G.; Farshad, M.; Widmer, J. A Novel Approach for Tetrahedral-Element-Based Finite Element Simulations of Anisotropic Hyperelastic Intervertebral Disc Behavior. Frontiers in Bioengineering and Biotechnology 2022, 10.

Widmer, J.; Aubin, C.-E.; van Lenthe, G. H.; Matsukawa, K. Editorial: Innovations to Improve Screw Fixation in Traumatology and Orthopedic Surgery. Frontiers in Bioengineering and Biotechnology 2022, 10.

Balzer, I.; Mühlemann, M.; Jokeit, M.; Rawal, I. S.; Snedeker, J. G.; Farshad, M.; Widmer, J. A Deep Learning Pipeline for Automatized Assessment of Spinal MRI. Computer Methods and Programs in Biomedicine Update2022, 2, 100081. https://doi.org/10.1016/j.cmpbup.2022.100081.

Tsagkaris, C.; Widmer, J.; Wanivenhaus, F.; Redaelli, A.; Lamartina, C.; Farshad, M. The Sitting vs Standing Spine. North American Spine Society Journal (NASSJ) 2022, 9, 100108. https://doi.org/10.1016/j.xnsj.2022.100108.

Cornaz, F.; Fasser, M.-R.; Snedeker, J. G.; Spirig, J. M.; Farshad, M.; Widmer, J. The Biomechanical Fundamentals of Crosslink-Augmentation in Posterior Spinal Instrumentation. Sci Rep 2022, 12 (1), 7621. https://doi.org/10.1038/s41598-022-11719-2.

Jokeit, M.; Kim, J. H.; Snedeker, J. G.; Farshad, M.; Widmer, J. Mesh-Based 3D Reconstruction from Bi-Planar Radiographs; 2022.

Haupt, S.; Cornaz, F.; Falkowski, A. L.; Widmer, J.; Farshad, M. Biomechanical Considerations of the Posterior Surgical Approach to the Lumbar Spine. The Spine Journal 2022. https://doi.org/10.1016/j.spinee.2022.08.006.

Cornaz, F.; Haupt, S.; Farshad, M.; Widmer, J. Real-Time Assessment of Anteroposterior Stability of Spinal Segments. Eur Spine J 2022, 31 (9), 2368–2376. https://doi.org/10.1007/s00586-022-07286-9.

Fasser, M.-R.; Gerber, G.; Passaplan, C.; Cornaz, F.; Snedeker, J. G.; Farshad, M.; Widmer, J. Computational Model Predicts Risk of Spinal Screw Loosening in Patients. Eur Spine J 2022, 31 (10), 2639–2649. https://doi.org/10.1007/s00586-022-07187-x.

Farshad, M.; Cornaz, F.; Spirig, J. M.; Sutter, R.; Farshad-Amacker, N. A.; Widmer, J. Spondylophyte Classification Based on Biomechanical Effects on Segmental Stiffness. The Spine Journal 2022, 22 (11), 1903–1912. https://doi.org/10.1016/j.spinee.2022.06.001.

Lindenmann, S.; Tsagkaris, C.; Farshad, M.; Widmer, J. Kinematics of the Cervical Spine Under Healthy and Degenerative Conditions: A Systematic Review. Ann Biomed Eng 2022, 50 (12), 1705–1733. https://doi.org/10.1007/s10439-022-03088-8.

Farshad, M.; Hagel, V.; Spirig, J. M.; Fasser, M.-R.; Widmer, J.; Burkhard, M. D.; Calek, A.-K. Biomechanics of Transforaminal Endoscopic Approaches. Spine (Phila Pa 1976) 2022, 47 (24), 1753–1760. https://doi.org/10.1097/BRS.0000000000004471.

Heggli, I.; Laux, C. J.; Mengis, T.; Karol, A.; Cornaz, F.; Herger, N.; Aradi‐Vegh, B.; Widmer, J.; Burkhard, M. D.; Farshad‐Amacker, N. A.; Pfammatter, S.; Wolski, W. E.; Brunner, F.; Distler, O.; Farshad, M.; Dudli, S. Modic Type 2 Changes Are Fibroinflammatory Changes with Complement System Involvement Adjacent to Degenerated Vertebral Endplates. JOR Spine 2022. https://doi.org/10.1002/jsp2.1237.

Tsagkaris, C.; Kalachanis, K.; Widmer, J.; Farshad, M. Spine Biomechanics in the Work of Aristotle (384 – 322 BC). Surg Innov 2022, 155335062211480. https://doi.org/10.1177/15533506221148012.

Tsagkaris, C.; Calek, A.-K.; Fasser, M.-R.; Spirig, J. M.; Caprara, S.; Farshad, M.; Widmer, J. Bone Density Optimized Pedicle Screw Insertion. Frontiers in Bioengineering and Biotechnology 2023, 11.

Burkhard, M. D.; Cornaz, F.; Spirig, J. M.; Wanivenhaus, F.; Fasser, M.-R.; Widmer, J.; Farshad, M. Residual Motion of Cortical versus Pedicle Screw Constructs after Decompression, Interbody Fusion and Cross-Link Augmentation. Eur Spine J 2023, 32 (4), 1401–1410. https://doi.org/10.1007/s00586-023-07596-6.

Burkhard, M. D.; Spirig, J. M.; Wanivenhaus, F.; Cornaz, F.; Fasser, M.-R.; Widmer, J.; Farshad, M. Residual Motion of Different Posterior Instrumentation and Interbody Fusion Constructs. Eur Spine J 2023, 32 (4), 1411–1420. https://doi.org/10.1007/s00586-023-07597-5.

Farshad, M.; Tsagkaris, C.; Widmer, J.; Fasser, M.-R.; Cornaz, F.; Calek, A.-K. Vertebropexy as a Semi-Rigid Ligamentous Alternative to Lumbar Spinal Fusion. Eur Spine J 2023, 32 (5), 1695–1703. https://doi.org/10.1007/s00586-023-07647-y.

Haupt, S.; Cornaz, F.; Falkowski, A. L.; Farshad, M.; Widmer, J. The Biomechanical Consequence of Posterior Interventions at the Thoracolumbar Spine on the Passively Stabilized Flexed Posture. Journal of Biomechanics2023, 153, 111599. https://doi.org/10.1016/j.jbiomech.2023.111599.

Burkhard, M. D.; Calek, A.-K.; Fasser, M.-R.; Cornaz, F.; Widmer, J.; Spirig, J. M.; Wanivenhaus, F.; Farshad, M. Biomechanics after Spinal Decompression and Posterior Instrumentation. Eur Spine J 2023, 32 (6), 1876–1886. https://doi.org/10.1007/s00586-023-07694-5.

Calek, A.-K.; Tsagkaris, C.; Fasser, M.-R.; Widmer, J.; Hagel, V.; Farshad, M. Biomechanical Limitations of Partial Pediculectomy in Endoscopic Spine Surgery. The Spine Journal 2023, 23 (7), 1088–1095. https://doi.org/10.1016/j.spinee.2023.02.005.

Calek, A.-K.; Altorfer, F.; Fasser, M.-R.; Widmer, J.; Farshad, M. Interspinous and Spinolaminar Synthetic Vertebropexy of the Lumbar Spine. Eur Spine J 2023, 32 (9), 3183–3191. https://doi.org/10.1007/s00586-023-07798-y.

Spirig, J. M.; Fasser, M.-R.; Widmer, J.; Wanivenhaus, F.; Laux, C. J.; Farshad, M.; Passaplan, C. Intraoperative Anteroposterior and Oblique Fluoroscopic Views for Detection of Mediolateral Pedicle Screw Misplacement in the Lumbar Spine: A Randomized Cadaveric Study. The Spine Journal 2023, 0 (0). https://doi.org/10.1016/j.spinee.2023.10.006.

Calek, A.-K.; Widmer, J.; Fasser, M.-R.; Farshad, M. Lumbar Vertebropexy after Unilateral Total Facetectomy. The Spine Journal 2023, 23 (11), 1730–1737. https://doi.org/10.1016/j.spinee.2023.07.005.

Calek, A.-K.; Cornaz, F.; Suter, M.; Fasser, M.-R.; Baumgartner, S.; Sager, P.; Farshad, M.; Widmer, J. Load Distribution on Intervertebral Cages with and without Posterior Instrumentation. Spine J 2023, S1529-9430(23)03485-X. https://doi.org/10.1016/j.spinee.2023.10.017.