Vertebropexy: Tendon-Based Alternative to Spinal Fusion
Spinal fusion remains a cornerstone in treating various degenerative spinal conditions. Despite its widespread use, it is associated with significant complications such as implant failure, pseudarthrosis, and adjacent segment disease (ASD). These issues contribute to reoperation rates of up to 40% and revision surgeries in approximately 30% of cases within 15 years, leading to diminished patient outcomes and substantial global healthcare costs.
Vertebropexy as a Novel Solution
In light of these limitations, vertebropexy has been developed as an innovative approach. This technique aims to stabilize degenerated spinal segments through ligamentous (tendon-based) fixation, preserving motion in non-targeted directions and potentially reducing the complications associated with rigid spinal fusion.
Ovine Animal Study
This study investigates the biological integration of tendon grafts in an ovine model:
The goal is to establish a standardized surgical procedure for implanting tendon allografts in the spine.
Methods:
- Two different vertebropexy techniques are implanted in separate lumbar segments.
Figure 1: Simulation of two tendon fixation techniques to the spinous processes of the spine.
- Evaluation timepoints: 3, 6, and 12 months
- Imaging and histological analysis to assess osseointegration and tendon-to-tendon healing within and around the spinous processes.
The findings from this study will provide crucial insights into the safety and efficacy of vertebropexy, ultimately aiming to develop a more effective alternative to spinal fusion.
Figure 2: Depiction of a segmental cut with tendon around spinous processes and fixation with suture material (left) and histology (right).
